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Conservation and divergence of bHLH genes in the calcisponge Sycon ciliatum.

Identifieur interne : 000102 ( France/Analysis ); précédent : 000101; suivant : 000103

Conservation and divergence of bHLH genes in the calcisponge Sycon ciliatum.

Auteurs : Sofia A V. Fortunato [Norvège] ; Michel Vervoort [France] ; Marcin Adamski [Australie] ; Maja Adamska [France]

Source :

RBID : Hal:hal-01472886

English descriptors

Abstract

Basic Helix-Loop-Helix (bHLH) genes encode a large family of eukaryotic transcription factors, categorized into six high-order groups: pan-eukaryotic group B involved in regulation of cell cycle, metabolism, and development; holozoan-specific groups C and F involved in development and maintenance of homeostasis; and metazoan-specific groups A, D and E including well-studied genes, such as Atonal, Twist and Hairy, with diverse developmental roles including control of morphogenesis and specification of neurons. Current scenarios of bHLH evolution in animals are mainly based on the bHLH gene set found in the genome of demosponge Amphimedon queenslandica. In this species, the majority of the 21 identified bHLH genes belong to group B, and the single group A gene is orthologous to several neurogenic bilaterian subfamilies, including atonal and neurogenin.


Url:
DOI: 10.1186/s13227-016-0060-8


Affiliations:


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Links to Exploration step

Hal:hal-01472886

Le document en format XML

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